![]() This hormone is best known for its crucial role in the bodily response to stress.Īt physiologically appropriate levels, cortisol is vital in maintaining normal sleep-wake cycles, and acts to increase blood sugar levels. Interestingly, the outer layer (cortex) of the adrenal glands has the distinct responsibility of producing cortisol. ![]() They have numerous functions such as the production of hormones called catecholamines, which includes epinephrine and norepinephrine. The adrenal glands are situated just above each kidney, and form part of the endocrine system. Endogenous causes include the elevated production of cortisol by the adrenal glands, while exogenous causes include the excessive use of cortisol or other similar steroid (glucocorticoid) hormones over a prolonged period of time. ![]() This may arise because of an endogenous or exogenous source of cortisol. Liji Thomas, MDĬushing's Syndrome (sometimes called hypercortisolism) is a hormonal disease caused by an abnormally high level of the hormone cortisol in the body. ![]() By Afsaneh Khetrapal, BSc Reviewed by Dr. ![]()
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